All issues > Volume 33(7); 1990

Original Article

J Korean Pediatr Soc. 1990;33(7):1009-1011. Published online July 31, 1990.

A Case of Congenital Hypofibrinogenemia.

Ji In Park¹, In Seok Lim¹, Chul Ha Kim¹, Byoung Hoon Yoo¹

¹Department of Pediatrics, College of Medicine, Chung Ang University, Seoul, Korea

Received: February 20, 1990;  Accepted: April 24, 1990.

Abstract

Congenital hypofibrinogenemia is a rare congenital bleeding disorder, inherited by autosomal dominant or recessive trait. We experienced one case of congenital hypofibrinogenemia in 4 year-old female patient with chief complaints of headache and ecchymosis. History of continuous umbilical cord bleeding and frequent bleeding tendency against minor trauma were revealed on her past medical history. On laboratory data, bleeding time, platelet aggregation test were normal and factor assays were all within normal limit. PT, aPTT were markedly prolongated and fibrinogen level was decreased to 23 mg/dl. Subdural hematoma and communicating hydrocephalus were detected on brain CT film. We report 1 case of congenital hypofibrinogenemia with a brief review of literatures.

Keywords :Congenital hypofibrinogenemia