All issues > Volume 33(5); 1990

Original Article

J Korean Pediatr Soc. 1990;33(5):658-665. Published online May 31, 1990.

A Clinical Study on Reye's Syndrome.

Myeong Hee Cha¹, Seong Hee Shin¹

¹Department of Pediatrics, Pusan Adventist Hospital, Pusan, Korea

Received: September 28, 1989;  Accepted: December 30, 1989.

Abstract

The auther analyzed the clinical features and prognosis of the 143 patients with Reye*s syndrome who were admitted at three hospital for 10 years from Jan. 1979 to Dec. 1988. The results were summarized as follows: 1) There was non significant difference in annual and seasonal incidence except slight higher incidence in 1981. 2) The male to female ratio was 1.4:1. The age distribution was from 3 months to 10 years, and most of the cases (81.2%) were under 3 years. The overall mortality rate was higher. 3) The prodromal illness were upper respiratory infection (65.7%), gastroenteritis and chickenpox. 4) The main clinical symptoms at admission were loss of consciousness (94.4%), nausea and vomiting (86.7%), convulsion (60.8%), hepatomegaly, fever, and hyperpnea. 5) According to the severity (Lovejoy’s classification), the 59.4% of cases were in Stage or above on admission and the cases were increased to 76.4% during admission. The mortality rate was 36.4% and most of death were within 72 hours from admission. The higher the stage, the higher the mortality rate.

Keywords :Reye’s syndrome