All issues > Volume 33(4); 1990

Original Article

J Korean Pediatr Soc. 1990;33(4):539-543. Published online April 30, 1990.

A case of Distal Renal Tubular Acidosis.

Seong Gyoo Park¹, Gyung Min Ann¹, Sang Hee Park¹, Kwang Chul Lee¹, Chang Sung Son¹, Pyung Hwa Choi¹

¹Department of Pediatrics, College of Medicine, Korea University, Seoul, Korea

Received: June 15, 1989;  Accepted: September 23, 1989.

Abstract

Distal Renal Tubular Acidosis is rare disease which is characterized by impaired renal acidification at distal renal tubule and collecting duct. The urinary pH cannot be reduced below 5.8 despite severe systemic acidosis. A 6 months old boy was admitted to Ped. Dept, of Korea University Hospital due to fever and tachypnea. IVP and abdominal sonography were normal. Laboratory data showed hyperchloremia and metabolic acidosis. In spite of these data, urine pH was relatively alkali. Confirmatory diagnosis was made by NaHCO3 loading test and NH4C1 loading test. Under the impression of distal renal tubular acidosis, alkali therapy was done. Thereafter, the patient was improved. We report a case of distal renal tubular acidosis with brief review of related literatures.

Keywords :Distal renal tubular acidosis, Renal acidification