All issues > Volume 33(2); 1990

Original Article

J Korean Pediatr Soc. 1990;33(2):212-219. Published online February 28, 1990.

Glucose-6 Phosphate Dehydrogenase Deficiency.

Meen Jai Lee¹, Sang Eun Lee¹, Dong Whan Lee¹, Sang Jhoo Lee¹, Sang Chul Park²

¹Department of Pediatrics, College of Medicine, Soon Chun Hyang University, Seoul, Korea
²Department of Biochemistry, College of Medicine, Seoul National University, Seoul, Korea

Received: June 29, 1989;  Accepted: September 19, 1989.

Abstract

Glucose-6-phosphate dehydrogenase(G-6PD) deficiency is the most common disease-producing enzyme deficiency of human beings, but extremely rare in Korea. Four well-characterized clinical syndromes are recognized: acute, oxidative stress(drug or infection) induced hemolytic anemia; neonatal hyperbilirubinemia; favism and chronic nonspherocytic hemolytic anemia. We have experi- enced a case of G-6PD deficiency in child associated with chronic hemolytic anemia and exacerba- tions of hemolysis by infection and drug administration. We made a brief review of related literature.

Keywords :G-6PD deficiency