All issues > Volume 33(2); 1990

Original Article

J Korean Pediatr Soc. 1990;33(2):205-211. Published online February 28, 1990.

A Case of Nonimmunologic Hydrops Fetalis Associated with Down Syndrome.

Sang Eun Lee¹, Meen Jai Lee¹, Dong Hwan Lee¹, Sang Jhoo Lee¹

¹Department of Pediatrics, College of Medicine, Soon Chun Hyang University, Seoul, Korea

Received: June 29, 1989;  Accepted: September 19, 1989.

Abstract

We experienced a case of nonimmunologic hydrops fetalis associated with Down syndrome. The patient had generalized edema with severe scrotal swelling and abdominal distension. A roentgenogram showed bilateral pleural effusion and ascites. The chromosomal study revealed 21 trisomy. On autopsy, there were pleural fluid and ascites as well as pericardial fluid. Small ASD and incomplete lobation of the right lung were detected. Chromosomal abnormalities should always be considered in the differential diagnosis of nonim- munologic hydrops fetalis in the fetus and neonate. Their features are often distorted by edema, thus obscuring the phenotypic characteristics of the common chromosomal abnormalities.

Keywords :Nonimmunologic hydrops fetalis, Chromosome, Down syndrome