All issues > Volume 33(2); 1990

Original Article

J Korean Pediatr Soc. 1990;33(2):196-204. Published online February 28, 1990.

The Clinical Observation on Mucocutaneous Lymph Node Syndrome.

Sang Yun Ahn¹, Ja Wook Koo¹, Ha Baik Lee¹, Soo Jee Moon¹, Hahng Lee¹

¹Department of Pediatrics, Hanyang University College of Medicine, Seoul, Korea

Received: August 7, 1989;  Accepted: November 1, 1989.

Abstract

The one-hundred-forty nine children with mucocutaneous lymph node syndrome who were diagnosed and treated through admission at the Department of Pediatrics, Hanyang University Hospital from July 1977 to January 1989, were investigated for clinical patterns and laboratory , correlations. The results are as follows: 1) Most patients (84.5%) were under 4 years of the age. 2) Boys were more prevalent than girls, as a ratio of 1.9:1. 3) Seasonal incidence was high in May to July and November to December, respectively. 4) The incidence of principal symptoms were fever lasted 8.9±3.7 days (91.3%), bilateral conjun- ctival injection (87.2%), skin rash (83.9%), changes in extremities (induration of palm and sole 77.9%, desquamation 73.8%), lip and oral mucosal change (73.8%) and cervical lymphadenopathy (72.5%) in order. 5) The main laboratory findings observed were positive CRP (97.2%), increased ESR (90.6%), leukocytosis (83.9%), pyuria (44.3%), thrombocytosis (43.1%), and anemia (40.3%). 6) In 67.8% of the patients, peak thrombocytosis appeared on the 8~13 days after onset of the disease. 7) Abnormal findings of the heart were found in 35.8% of the patients by ECG and 14% by echocardiogram, respectively. 8) Enlargement of the gallbladder was detected in 6 (33.3%) of 18 patients on abdominal ultrasono- gragphy. 9) Among 50 cases assessed by two-dimensional echocardiography, the abnormal findings were present in 6 of 34 cases (17.6%) in the aspirin treated group, as compared with 1 of 16 (6.3%) in the aspirin and intravenous gamma-globulintreated group.

Keywords :Mucocutaneous lymph node syndrome