All issues > Volume 33(1); 1990

Original Article

J Korean Pediatr Soc. 1990;33(1):129-134. Published online January 31, 1990.

Two Cases of Goitrous Hypothyroidism in Siblings.

Kwang Ok Lee¹, Hwa Il Kwag¹, Hoon Kook¹, Young Youn Choi¹, Tai Joo Hwang¹

¹Department of pediatrics, Chonnam University Hospital, Kwang Ju, Korea

Received: June 15, 1989;  Accepted: June 15, 1989.

Abstract

The authors experienced two cases of goitrous hypothyroidism in siblings. The etiology was considered to be defect of iodide organification in steps of thyroxine synthesis. The diagnosis was made on the basis of history, clinical features, thyroid function test, thyroid scanning, ultrasonogram and perchlorate discharge test. We report these cases with a review of related literatres.

Keywords :Goitrous hypothyroidism, defect of iodide organification