All issues > Volume 33(1); 1990

Original Article

J Korean Pediatr Soc. 1990;33(1):35-41. Published online January 31, 1990.

A Clinical Study of Staphylococcus Aureus Infection in Children.

Yong Joon Shin¹, Young Pyo Chang¹, Dong Kyu Jin¹, Byung Kiu Park¹, Hoan Jong Lee¹, Hyung Ro Moon¹

¹Department of Pediatrics, College of Medicine, Seoul National University, Seoul, Korea

Received: September 20, 1989;  Accepted: September 20, 1989.

Abstract

We reviewed 113 patients with Staphylococcus aureus infection and 219 strains of Staphylococcus aureus isolated from pediatric patients of Seoul National University Hospital from Jan. 1, 1987 to Dec. 31, 1987. The results were as follows: 1) The proportion of MSSA was 50.2% of total Staphylococcus aureus isolated and that of MRSA was 49.8%. Staphylococcus aureus were isolated from pus (33.8%), urine (16.9%), ear discharge (8. 2%), and blood (7.8%) etc. 2) Frequencies for specific type of infection were skin and soft tissue infection 34.4%, wound infection 10.4%, sepsis 9.6% and pneumonia 8.8% etc. Hospital acquired infections and community acquired infections were 43 and 82 cases respectively. 3) In MRSA infections, previous antiviotic use was a most important predisposing factor and others were presence of surgical wound, congenital heart disease and immunocompromised host etc. 4) Antibiotic sensitivity of MSSA was 100% for vancomycin, 97% for cephalothin, 91% for clindamycin, 80% for chloramphenicol, 68% for erythromycin and 63% for gentamicin etc. That of MRSA was 100% for vancomycin, 62% for clindamycin, 57% for chloramphenicol, 30% for eryth- romycin, 28% for gentamicin and 20% for cephalothin etc.

Keywords :Staphylococcus aureus, Methicillin sensitive Staphylococus aureus, Methicillin resistant Staphylococcus aureus