All issues > Volume 32(12); 1989

Original Article

J Korean Pediatr Soc. 1989;32(12):1726-1731. Published online December 31, 1989.

2 Cases of Intracranial Hemorrhae due to Late Hemorrhagic Disease of Infancy due to Vitamin K Deficiency.

Bong Hyune Chung¹, Hee Jung Seo¹, Young Hee You¹, Hyung Sook Lee¹

¹Department of Pediatrics, Korea Veterans Hospital, Seoul, Korea

Received: March 14, 1989;  Accepted: July 28, 1989.

Abstract

A clinical study was done on 2 cases under the diagnosis of late hemorrhagic disease of infancy due to Vitamin K dependent factor deficiency. The following results were obtained. The disorder occured most frequently during early infancy (40 days of age & 2 months of age) with male predominance (2 cases all are male). G-I tract, skin, CNS were the most common site of bleeding. Anemia, probably due to blood loss, was seen in all. Initial laboratory findings showed prolonged PT & PTT with normal platelets count in all cases. After Vitamin K therapy, PT & PTT became normal. Promptly response to Vitamin Kj therapy within 24 hrs was noted. And they were complete recovery from first pisode within 2 weeks after admition without reccurence.

Keywords :Intracranial hemorrhage due to late hemorrhagic disease of infancy