All issues > Volume 32(10); 1989

Original Article

J Korean Pediatr Soc. 1989;32(10):1416-1421. Published online October 31, 1989.

Angiolymphoid Hyperplasia with Eosinophilial: Kiruma's disease.

Choong Won Lee¹, Young Sik Kim¹, Soon Ki Kim¹, Il Soo Ha¹, Hyo Seop Ahn¹, Je Geun Chi², Il Han Kim³

¹Department of Pediatrics, College of Medicine, Seoul National University, Seoul, Korea
²Department of Pathology, College of Medicine, Seoul National University, Seoul, Korea
³Department of Therapeutic Radiology, College of Medicine, Seoul National University, Seoul, Korea

Received: July 14, 1988;  Accepted: July 14, 1988.

Abstract

Kimura’s disease is a rare, benign disease characterized by single or multiple subcutaneous nodules, eosinophilia and distinctive histopathologic features. Seven cases of Kimura’s disease under 15 yeaps of age who were admitted to the Dept, of Pediatrics, Seoul National University Hospital from Apr. 1983 to July 1987 were reviewed. The results were as follows: 1) The lesions were noted between the ages of 28 months and 15 years. 2) Chief complaints were eyelid edema, submandibular & postauricular mass, fever, and general- ized lymphadenopathy. 3) Lymphadenopathy was found in all cases. 4) Eosinophilia in the peripheral blood was found in five cases. 5) Two of the seven cases were improved with prednisolone alone. 6) Five of the seven cases were treated with mass excision and prednisolone. One was lost to follow up, one was improved with prednisolone alone, and three recurred but improved after radiotherapy.

Keywords :Angiolymphoid hyperplasia, Kimura’s disease, Eosinophilia