All issues > Volume 32(10); 1989

Original Article

J Korean Pediatr Soc. 1989;32(10):1397-1401. Published online October 31, 1989.

Study on Antithyroid Antibody and Thyroid Functional Status in Patients with Turner Syndrome.

Bo Young Lee¹, Duk Hi Kim¹, Kir Young Kim¹

¹Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea

Received: April 24, 1989;  Accepted: July 3, 1989.

Abstract

This study is a systematic cytogenetic and clinico-hormonal analysis of 26 cases who were diagnosed as Turner syndrome at the Yonsei Medical Center from Jan. 1978 to Jan. 1988. Antithyroid antibody and thyroid function tests were performed in Turner syndrome(3 groups according to karyotypes) and control group. The results were as follows: 1) The incidence of positive antithyroid antibody in the 26 cases was 42.3% and was greater than that in control group. There was no difference among the 3 groups. 2) While the rate of euthyroidism was 73.0%, rates for hypothyroidism and hyperthyroidism were 19.2% and 7.8% respectively. There was no difference among the 3 groups. 3) There were positive antithyroid antibodies in 11 cases and 9 cases (81.8%) of these were clinically normal and 2(18.2%) had hyperthyroidism. 4) There were thyroid abnormalities in 53.8% of the 26 cases and 92.3% of these were clinically normal. Thus, Patients with Turner syndrome must be evaluated for antithyroid antibody and thyroid functional status.

Keywords :Turner Syndrome, Antithyroid Antibody, Thyroid Function Test