All issues > Volume 32(8); 1989

Original Article

J Korean Pediatr Soc. 1989;32(8):1037-1044. Published online August 31, 1989.

Change of Cerebral Blood Flow Velocity in Normal Newborn Infants.

Sang Hee Kim¹, Se Jin Kang¹, Chang Sung Son¹, Pyung Hwa Choe¹, Nam Joon Lee²

¹Department of Pediatrics, College of Medicine, Korea University, Seoul, Korea
²Department of Radiology, College of Medicine, Korea University, Seoul, Korea

Received: July 10, 1989;  Accepted: July 10, 1989.

Abstract

The purpose of this study was to determine the cerebral hemodynamic change in normal newborn infant before and after ductal closure. The measurements of cerebral blood flow velocity of internal carotid artery, middle cerebral artery and anterior cerebral artery were obtained using a 5 MHzpulsed wave Doppler and pulsatility indices were calculated from the Pourcelot index in 15 normal fullterm newborn infants. The newborn infants were bom at Korea University Hospital from June 1 to August 31, the mean birth weight was 3.45 ±0.41 kg and the mean gestational age 39.7 ±1.5 weeks. The results were as follows. 1) Color and pulsed wave Doppler demonstrated reverse ductal flow in 15 of 15 infants at the first examination (mean age 5.8±2.7 hours) and the second study was performed at a mean time 35.6±13. 1 hours when ductal flow was no longer demonstrable in the pulmonary artery. 2) Ductal closure was associated with a significant decrease in pulsatility indices in internal carotid artery, middle cerebral artery and anterior cerebral artery (p< 0.001). 3) The increase in the diastolic velocity of internal carotid artery, middle cerebral artery and anterior cerebral artery was statistically significant (p< 0.001). 4) The systolic velocity of internal carotid artery was increased significantly (p<0.05), but the increase of reminders were not significant. 5) The mean blood pressure measured after ductal closure in riht arm was slightly increased but not significant statistically.

Keywords :Pulsatility Index