All issues > Volume 32(6); 1989

Original Article

J Korean Pediatr Soc. 1989;32(6):816-822. Published online June 30, 1989.

Clinical Observation and Electroencephalographic Findings relatee to Prognostic factor in Neonatal Seizure.

Soo Chun Kim¹, Jung Sam Jeon¹, Chong Woo Bae¹, Sa Joon Chung¹, Chang Il Ahn¹

¹Department of Pediatrics, College of Medicine, Kyung Hee University, Seoul, Korea

Received: October 27, 1988;  Accepted: December 9, 1988.

Abstract

To study the clinical prognosis of the neonatal seizure, we carried out a retrospective review on medical records of 40 neonates who were admitted to the Dept. of Pediatrics, Kyung Hee University Hospital between January 1979 and December 1986. The results from the study are summarized as follows 1) Male to female ratio were 1.8:1. In 50.0%(20/40) of newborn infants, neonatal seizure was detected under 7 days of age, in 17.5% by 21 days of age, in 32.5% by 28 days of age. 2) The etiologic classifications of neonatal seizure were hypoxic ischemic encephalopathy (18 cases, 45%), hypocalcemia (7 cases, 17.5%), intracranial hemorrhage (6 cases, 15%), developmental defect (4 cases, 10%), infection (3 cases, 7.5%) and hypoglycemia (2 cases, 5.0%). 3) Neonatal seizures may be classified into several types including generalized tonic (17 cases, 42. 5%), subtle (12 cases, 30%), multifocal clonic (4 cases, 10%), focal clonic (4 cases, 10%) and myoclonic attacks (3 cases, 7.5%). 4) The EEG findings were abnormal in 19 cases (47.5%). 5) In relapsing cases (10 cases, 25%), male to female ratio were 0.4: 1. 6) According to etiologic classification, relapsing rates were 100% in developmental defect, 33.3% in intracranial hemorrhage and infection, 16.7% in hypoxic ischemic encephalopathy. 7) In relapsing cases, the EEG findings was abnormal in 9 cases (90.0%).

Keywords :Neonatal seizure, Prognosis, EEG