All issues > Volume 32(6); 1989

Original Article

J Korean Pediatr Soc. 1989;32(6):779-788. Published online June 30, 1989.

A Clinical Study on Children with Acute Glomerulonephritis.

Jeong Ok Kim¹, Son Moon Shin¹, Yong Hoon Park¹

¹Department of Pediatrics, College of Medicine, Yeungnam University, Taegu, Korea.

Received: November 25, 1988;  Accepted: November 25, 1988.

Abstract

A clinical observation has been made on 111 children with acute glomerulonephritis who were admitted to Pediatric Department of Yeungnam University Hospital during 5 years period from June 1, 1983 to May 31, 1988. The incidence of acute glomerulonephritis among hospitalized patients was 1.59% and the annual incidence was decreased markedly after June 1986. Peak incidence was noticed in the wintertime from November to January when URI was most prevalent and male to female ratio was 1.7: 1. Most cases were between 7 to 9 years of age but cases below 3 years of age were quite infrequent. URI was the most common preceding illness(64.0%). Common clinical findings were edema(74%), gross hematuria(50.5%) and hypertension(44.1 %). At the time of admission, proteinuria was detected in 65.8%, granular cast in 54.1 %, RBC cast in 19.8% and almost all cases except 3 showed microscopic hematuria. ASO titer over 300 Todd units was found in 55.0%. Throat culture revealed group A β-hemolytic streptococcus in 15.3% of cases. C3 and C4 levels were reduced in 82.9% and 27.9% of cases and were normalized within 6 weeks and 4 weeks in most cases respectively. Electrolyte imbalance was accompanied in 33 cases, acute renal failure in 6 cases, hypertensive encephalopathy in 5 cases, congestive heart failure in 2 cases and nephrotic syndrome in 2 cases as the complication of acute glomerulonephritis. As a result of alternate penicillin adminstration to the suspected acute postinfectious glomerulonephritis, there is little evidence that penicillin affect the process of clinical and laboratory findings occured in acute phase

Keywords :Acute glomerulonephritis, Annual incidence, Penicillin administration