All issues > Volume 32(5); 1989

Original Article

J Korean Pediatr Soc. 1989;32(5):644-652. Published online May 31, 1989.

Hypercalciuria in Children with Hematuria.

Tae Sung Ko¹, Chang Youn Lee¹, Young Seo Park¹, Hae Il Cheong¹, Yong Choi¹, Kwang Wook Ko¹

¹Department of Pediatrics, College of Medicine， Seoul National University， Seoul, Korea

Received: November 2, 1988;  Accepted: November 2, 1988.

Abstract

Ten children with gross hematuria were diagnosed as hypercalciuria in the Department of Pediatrics, Seoul National University Children’s Hospital during the period from June 1983 to Aug. 1987. We reviewed their clinical data, retrospectively, and could obtain the following results. 1) The age at the onset of gross hematuria ranged from 4 months to 10 7/12 years, and the male to female ratio was 4:1 2) All patients had experienced recurrent gross hematuria before the diagnosis, and the hematuria was induced and exacerbated after physical exercise in 4 cases. Three children had a past medical history of urinary stone(s), and four had a dietary history of high calcium intake 3) The average amount of urine calcium excretion was 7.9 ± 3.2 mg/ kg/ day(4.2 -14.4 mg/ kg/day), and the average urinary calcium( mg/ dl) to creatinine( mg/ dl) ratio was 0.49 ± 0.24(0.24 - 1.02). 4) Calcium loading tests were executed in 6 cases, and 4 cases were ascertained as renal leak type and 2 cases as absorptive type. The latter 2 cases had a history of high calcium intake. 5) All patients showed improvement in urinary calcium excretion and hematuria with low salt(low calcium) diet with or without hydrochlorothiazide. In conclusion, hypercalciuria should be considered in the differential diagnosis of hematuria in children. It can be diagnosed easily by measuring urine calcium and creatinine without any invasive studies. After then, appropriate medical managements are recommended to manage hematuria effectively and even to prevent the formation of subsequent urinary tract calculi.

Keywords :Hematuria, Hypercalciuria