All issues > Volume 32(4); 1989

Original Article

J Korean Pediatr Soc. 1989;32(4):567-575. Published online April 30, 1989.

A Case of Virus Associated Hemophagocytic Syndrome.

Yang Soo Kang¹, Ue Chong Yang¹, Hae Il Cheoung¹, Ho Jin Park¹, Mi Ja Shin¹, Je Geun Chi²

¹Department of Pediatrics, Seoul Red Cross Hospital, Seoul, Korea
²Department of Pathology, College of Medicine, Seoul National University, Seoul, Korea

Received: July 18, 1988;  Accepted: October 20, 1988.

Abstract

Virus associated hemophagocytic syndrome is a rare hemophagocytic disorder, apparently associated with active viral infection, apparently associated with active viral infection, in which reactive histiocytes proliferate in the reticuloendothelial system, mainly bone marrow and medullary portions of lymph nodes, as a non-malignant, reversible but potentially constitutional symptoms with high fever and hepatosplenomegaly and by laboratory findings of pancytopenia, hemophagocytosis, abnormal liver function and coagulopathy. Inappropriate immunosuppressive or cytotoxic therapy of the hemophagocytic syndrome may increase the risk of a fatal outcome. The authors experienced and report a case of virus associated hemophagocytic syndrome, who was estimated 8 months old male infant, with the review of the literatures.

Keywords :Virus associated hemophagocytic syndrome