All issues > Volume 32(4); 1989

Original Article

J Korean Pediatr Soc. 1989;32(4):500-510. Published online April 30, 1989.

Clinical Study of Encephalitis and Encephalopathy in Children.

Dong Hunb Lee¹, Soo Chun Kim¹, Sa Jun Chung¹, Chang Il Ahn¹

¹Department of Pediatrics, College of Medicine, Kyung Hee University, Seoul, Korea

Received: August 16, 1988;  Accepted: October 6, 1988.

Abstract

This study was undertaken to evaluate the electronencephalographic and clinical findings in 132 cases of encephalitis and encephalopathy in the Department of Pediatrics, Kyung Hee University Hospital for 9 years from Jan. 1979 to Dec. 1987. The results were summerized as follows; 1) The incidence of ecephalitis was 0.46%{86 cases) and the incidence of encephalopathy was 0.25 % (46 cases) among total in-patient (18,671). 2) Male to female ratio was 1.6:1 in encephalitis and 1.3:1 encephalopathy and the peak age was 2 to 6 years in both. 3) Autumn was the most prevalent season (45.3% in encephalitis and 37.0% in encephalopathy) and late summer was the 2nd most common (2.3% in encephalitis and 19.6% in encephalopathy). 4) In etiologies, unknown cases were 58.1 % in ecephalitis and 73.9% in encephalopathy and Japanese B encepahlitis was the most common cause (23.2%) among the known etiologies of encepha. litis. 5) In clinical symptoms and signs, Encephalitis; changes of consciousness (91.9%), seizure (67.4%), fever (58.1%)'" Encephalopathy; changes of consciousness (95.7%), seizure (76.1%), fever (58.7%)'" 이 CSF pleocytosis was found in 96.2% of encephalitis but not in all of encephalopathy and CSF protein values were elevated in 50.6% of ecephalitis and only in 18.6% of encephalopathy and CSF glucose value was decreased in 30.4% of encephalitis and 23.2% of encephalopathy. 7) In brain CT findings, Encephalitis; unremarkable findings (30.5%), brain swelling (30.5%), low density (16.7%)' " Encephalopathy; unremarkable findings (43.5%), brain swelling (30.4%), low density (13.0%) .. ' 8) In the EEG findings, abnormal EEG findings was observed in 81.8 of encephalitis and 81.0% of encephalopathy. 9) In the relationship between EEG findings and prognosis, mortality rate was 11.4% in patients with abnormal EEG findings on admission and the highest mortality rate was observed in patients with EEG findings of suppression pattern among the abnormal EEG findings on admission{50.0%).

Keywords :Encephalitis, Encephalopathy, EEG