All issues > Volume 32(1); 1989

Original Article

J Korean Pediatr Soc. 1989;32(1):130-136. Published online January 31, 1989.

A Case of Malignant Ependymoma.

Ja Wook Koo¹, Sun Ho Lee¹, In Joon Seol¹, Hahng Lee¹

¹Department of Pediatrics, College of Medicine, Hanyang University, Seoul, Korea

Received: May 2, 1988;  Accepted: July 15, 1988.

Abstract

Intracranial tumors presenting in the first year of life are uncommon. Brain tumors in infancy are predominantly supratentorial, whereas in older children the majority are infratentorial. Malignant ependymoma is a rare type of primitive ependymal tumor with clinically high malignancy. We experienced a malignant ependymoma in a 5 month old girl who had progressive enlargement of head circumference with vomiting. Brain computed tomography revealed a 10 x 10 cm sized mass in left parietotemporal area of the cerebral hemisphere with multiple punctate calcifications along the outer margin of the mass. Diagnosis was confirmed by histologic examination of the tumor tissue On microscopic examination the tumor was well circumscribed and fairly cellular. The tumor cells were polygonal or elongated with regular round nuclei and delicate chromatin pattern. In areas perivascular pseudorosette as well as numerous mitoses and multifocal necrosis were presented. We present a case of malignant ependymoma with the brief review of related literatures.

Keywords :Malignant ependymoma