All issues > Volume 31(12); 1988

Original Article

J Korean Pediatr Soc. 1988;31(12):1689-1695. Published online December 31, 1988.

A Case of Addison's Disease.

In Hoon Lee¹, H. D. Lee¹, Hee Ju Jeon¹, Chan Yung Kim¹

¹Department of Pediatrics, College of Medicine Pusan National University, Pusan, Korea

Received: April 18, 1988;  Accepted: June 24, 1988.

Abstract

A 9-year-old girl with Addison’s disease without other endocrine disorder presented with a brief review of the literature. The patient was transferee! to our hospital because of darkish brown pigmentation of whole body and generalized weakness which had misunderstood cyanotic heart disease. On physical examination, she was poorly nourished and below 10 percentile in weight and height. Skin and mucous membrane were diffusely darkish brown, especially over the face, fingertips, toetips and gingiva. Laboratory studies showed low serum cortisol, high ACTH concentration, low Na/K ratio and low 24 hours urinary 17-hydroxycorticoids, but 8 hours intravenous ACTH stimulation test failed to rise the plasma cortisol and 24 hours urinary 17-hydroxycorticoids level.

Keywords :Addison’s disease, Chronic adrenal insufficiency