All issues > Volume 31(10); 1988

Original Article

J Korean Pediatr Soc. 1988;31(10):1376-1380. Published online October 31, 1988.

A Case of Dapsone Syndrome.

Jeong Kyu Seoh¹, Hye Kyong Bae¹, Jae Seung Yang¹, Eung Deok Choi¹, Baek Keun Lim¹, Jong Soo Kim¹

¹Department of Pediatrics, Yonsei University, Wonju College of Medicine, Wonju, Korea

Received: April 1, 1988;  Accepted: April 25, 1988.

Abstract

Dapsone syndrome is a rare hypersensitivity reaction to Dapsone. The reaction included fever, malaise, dermatitis jaundice with hepatic dysfunction, lymphadenopathy, and hemolytic anemia. We have experienced a case of Dapsone syndrome in a 10 years old male. This patients had taken D.D.S. with 50 mg per day for 1 month to treat an unknown skin disease. After then, above mentioned symptoms and signs were developed. All of the main features of the Dapsone Syndrome were present in this case, and none of the clinical and laboratory findings were incompatible with this diagnosis. A brief review of the related literature is presented.

Keywords :Dapsone, Dapsone syndrome