All issues > Volume 31(6); 1988

Original Article

J Korean Pediatr Soc. 1988;31(6):772-778. Published online June 30, 1988.

Endodermal Sinus Tumor in Children.

Jae Sun Jung¹, Hyo Seop Ahn², Chang Yee Hong²

¹Department of Pediatrics, Seoul City Youngdungpo Hospital, Seoul, Korea
²Department of Pediatrics, College of Medicine, Seoul National University, Seoul, Korea

Received: November 30, 1987;  Accepted: January 5, 1988.

Abstract

Thirty-three cases of endodermal sinus tumor were reviewed. They were diagnosed at Seoul National University Hospital over the last 9 years. Sixteen were testicular, 12 were sacrococcygeal and the others were mediastinal, vaginal, ovarian, retrovesical and tongue endodermal sinus tumor. Endodermal sinus tumor of the tongue was the first reported case in the world. Serum 公-fetoprotein of 32 cases was elevated at diagnosis and well correlated with clinical course. In testicular endodermal sinus tumor 9 were treated by inguinal orchiectomy: 3 were relapse free for more than 2 years, but 2 cases were relapsed. The other 7 cases were treated by inguinal orchiectomy and cheomtherapy with or without radiotherapy: 3 of them were relapse free for more than 2 years after completion of chemotherapy but 2 were relapsed. Further study with larger series is required to evaluate the optimal treatment of testicular endodermal sinus tumor.

Keywords :Endodermal sinus tumor, Yolk sac tumor