All issues > Volume 31(6); 1988

Original Article

J Korean Pediatr Soc. 1988;31(6):754-761. Published online June 30, 1988.

Normal TSH Levels in Neonates by TSH Screening test.

Jae Won Song¹, Jong Lin Rhi¹, Sei Won Yang¹, Jung Hwan Choi¹, Chong Ku Yun¹, Hyung Ro Moon¹, Bo Youn Cho², Chang Soon Koh²

¹Department of Pediatrics, College of Medicine, Seoul National University, Seoul, Korea
²Department of Internal Medicine, College of Medicine, Seoul National University, Seoul, Korea

Received: November 13, 1987;  Accepted: January 6, 1988.

Abstract

In 110 term neonates without perinatal problems who were bom in SNUH, blood TSH levels were measured by TSH screening test for congenital hypothyroidism. The results are as follows 1) Normal TSH level was 14.8±7.8 µU/ml, 8.8±4.7 µU/ml, and 6.5±2.7 µU/ml in neonates of age 0 〜24 hours, 24—48 hours, and 48〜72 hours respectively, and all TSH values in neonates of age 48〜72 hours were below 15 µU/ml. 2) There was no significant difference in TSH level between male and female and types of delivery, and TSH value did not correlate with birth weight. 3) In fullterm neonates bom in SNUH, the cutoff point of TSH level at age 48〜72 hours was 15 µU/ml, and so if TSH value was above this level as screening procedure, recall for serum sampling and clinical evaluation for congenital hypothyroidism would be required.

Keywords :TSH, Neonatal screening, Congenital hypothyroidism