All issues > Volume 31(6); 1988

Original Article

J Korean Pediatr Soc. 1988;31(6):700-706. Published online June 30, 1988.

Clinical Observation of Human Rota Virus(HRV) Gastroenteritis.

Kee Don Hong¹, Gil Hyun Kim¹, Jae Ock Park¹, Sang Jhoo Lee¹

¹Department of Pediatrics, College of Medicine, Soon Chun Hyang University, Seoul, Korea

Received: November 9, 1987;  Accepted: January 6, 1988.

Abstract

This study was done with the 96 patients with watery diarrhea from Oct. to Nov. 1986. ELISA study was done to detect Human Rota Virus antigen for all patients. Clinical and laboratory comparision were made between HRV antigen positive group and HRV antigen negative group. The results were as follows: 1) HRV antigen was detected in 62 patients (64.6%) among 96 patients of diarrhea or vomiting. 2) HRV antigen was detected in 59 patients (95.2%) under the age of 24 months. 3) Mean age of HRV positive patients was 12.7±3.4 months. 4) Mean duration of diarrhea was 6.3±1.9 days in HRV antigen positive group and 5.1 ±2.5 days in non HRV group. 5) Vomiting (75.8%) 47cases, diarrhea (100%) 62 cases and dehydration (87.1%) 54 cases were noted in HRV antigen positive group, Which was higher than in non HRV group. 6) Positive rate for HRV antigen was 41.3% in the breast fed and 58.7% in formula fed infants below 13 months of age. 7) There were no differences in number of vomiting, diarrhea and duration of diarrhea and hospitalization between two groups. 8) There were no differences in laboratory data except leukocytosis, which was prominent in HRV antigen positive group.

Keywords :Human rotavirus gastroenteritis, ELISA