All issues > Volume 31(4); 1988

Original Article

J Korean Pediatr Soc. 1988;31(4):511-518. Published online April 30, 1988.

A Case of Thrombotic Thrombocytopenic Purpura in Childhood.

Dong Kun Hyun¹, Jung Bae Lee¹, Chang Hyun Yang¹, Kir Young Kim¹

¹Department of Pediatrics, Yonsei University, College of Medicine, Seoul, Korea

Received: September 5, 1987;  Accepted: November 20, 1987.

Abstract

Thrombotic thrombocytopenic purpura is clinically characterized by microangiopathic hemolytic anemia, thrombocytopenia, fever, renal disorder and transient bizarre neurological symptoms. Its essential histological lesion consists of numerous complete or, more often, incomplete occlusions of the arterioles and capillaries by hyaline material. We have experienced a case of thrombotic thrombocytopenic purpura in infancy. The patient was a one year and 4 month-old who complains petechiae on the whole body since birth and generalized tonic convulsion with eyeball deviation 20 days before admission. She showed microangiopathic hemolytic anemia, thrombocytopenia on laboratory findings and cerebral infarction on right frontoparietal area on brain C-T scan. We diagnosed her thrombotic thrombocytopenic purpura and presented a brief review of literature.

Keywords :Thrombotic Thrombocytopenic Purpura