All issues > Volume 31(3); 1988

Original Article

J Korean Pediatr Soc. 1988;31(3):306-314. Published online March 31, 1988.

A Clinical Review of Congenital Anomalies in Neonates.

Chan Gyoo Hwang¹, Byung Ho Lim¹, Ki Bok Kim¹

¹Department of Pediatrics, Kwangju Christian Hospital, Kwangju, Korea

Received: November 10, 1987;

Abstract

A study was made on the incidence of malformation among 8959 babies delivered at Kwangju Christian Hospital during a period of three years starting from June 1983. The results are summarized as follows: 1) Of 8959 newborns 243 babies (2.7%) were found to have some form of malformation. The incidence was 3.0% for male and 2.3% for female, but no significant difference between both sexes was noted. 2) Of 789 low-birth-weight infants, 39 (4.9%) were malformed, wherease among 8170 full-term infants 204 babies (2.5%) had malformations, indicating that low-birth-weight infants have hgiher incidence of malformation (P<0.01). 3) Theincidence of malformation was not related with the number of parity (P<0.1). 4) Among 8796 liver-bom infants, 232 (2.6%) had malformations, wherease 11 (6.7%) were found anomalous among 163 still-bom babies, revealing significantly higher incidence in the la竹er group (P<0.01). 5) 2.7% of babies bom to mothers younger than 35 years of age had malformations, wherease mothers older than 35 years delivered anomalous babies in 3.2%, but there was no significant difference between both groups (P>0.1). 6) The incidence of malformation seems to be related to the length of gestational period, as 4.1% of babies who had bad a gestational period less than 38 weeks had malformations, while 2.6% of infants who had had a gestation longer than 38 weeks were malformed (P<0.05). 7) Of 243 malformed babies 29 (11.9%) had multiple malformation, most commonly involving two separate organs. The organs involved were in descending order of frequency: the musculoskeletal, gastrointestinal, cutaneous, genitourinary, cardiovascular, central nervous, and the respiratory sys- tem. 8) Classified according to Marden, the severe form, with 1,95%, predominate over the mile form (1.35%). 9) Twenty six of the malformed infants (10.7%) were either stillborn or dead on delivery, and anencephaly was the most common malformation among them.

Keywords :Congenital Malformations