All issues > Volume 31(1); 1988

Original Article

J Korean Pediatr Soc. 1988;31(1):72-77. Published online January 31, 1988.

Clinical Analysis of Congenital Malformations in the Newborn Infant.

Hoon Chang¹, Chae Hwa Lee¹, In Kyung Sung¹, Byung Churl Lee¹, Sung Hoon Cho¹

¹Department of Pediatrics, Catholic University Medical College, Seoul, Korea

Received: September 23, 1987;

Abstract

Congenital malformations are still one of the leading problems of neonatal death and illness. But, we have only a few data for about it, because of difficulty in the exact analysis of the incidence and etiologic factors. During the period of 6 years, between January 1980 and December 1985, a clinical study about the general incidence of congenital malformations was done on 50, 979 live borns delivered at 7 hospitals of Catholic Medical Center. The results were as follows: 1) The incidence of congenital malformations was 2.1% and the frequency of male congenital malformations was 2.3% and that of females was 1.8%. 2) The incidence of malformations in low birth weight infants (4.0%) was higher than that of normal (1.9%) and high birth weight infants (1.6%). 3) In the prematures below 37 weeks, malformations occured more frequently than in the mature infants above 37 weeks (4.5% vs 1.9%). 4) The incidence of malformations was 2.0% and 2.8% in below and above 35 years of maternal age groups, respectably. 5) Among 1,050 malformed infants, 277 (26.4%) had more than one malformation. 6) Gastrointestinal system was the most frequently involved system (24.4%) and then musculo- skeletal system, skin, cardiovascular system in the order. 7) The most frequently involved system which caused the neonatal death was central nervous system (39.8% of 191 total death). 8) Major congenital malformations were 64.8% and minor malformations were 35.2%.

Keywords :Congenital malformations.