All issues > Volume 31(1); 1988

Original Article

J Korean Pediatr Soc. 1988;31(1):22-28. Published online January 31, 1988.

Analysis for Causative Agents in Neonatal Sepsis.

Jung Sook Hong¹, Ki Ji Lee¹, Shul Hoe Koo¹, Yun Joo Cheung¹

¹Department of Pediatrics, Kosin Medical College, Gospel Hospital, Busan, Korea

Received: August 28, 1987;

Abstract

To determine causative organisms and their antibitotics sensitivities in neonatal sepsis, we made a review on the 26 cases of neonatal sepsis. Patients were admitted to the special care nursery of Gospel hospital of Kosin Medical College during the period of 2 years from January 1985 to December 1986 and the results were: 1) The most frequently growing organism was Staphylococcus epidermidis (34.6%) and drugs of choice were cephalothin and vancomycin with the sensitivities of over 90%. The sensitivity of methicillin was 38%. 2) The significant predisposing factors were TPN and instrumentation, especially among the Staphylococcus epidermidis sepsis. 3) Staphylococcus aureus grew out in the blood from the outboms and its incidence was 30.8% of all patients. 4) Amikacin was the drug of choice when gram negative rods were suspected for the cause of sepsis.

Keywords :Neonatal sepsis