All issues > Volume 30(10); 1987

Original Article

J Korean Pediatr Soc. 1987;30(10):1107-1114. Published online October 31, 1987.

Clinical Observation and Study for Cerebrospinal Fluid Protein Levels in Aseptic Meningitis.

D H Chee¹, M I Lee¹, S H Kim¹, K C Sohn¹

¹Department of Pediatrics, National Medical Center, Seoul, Korea

Abstract

Observation for clinical findings and laboratory findings, especially for cerebrosipinal fluid protein level has been done in 57 cases of aseptic meningitis who had been admitted to pediatric dept, of National Medical Center from Jan. ’81 to May ’85. The results were as follows; 1) The ratio of male to female was 1.7:1, and the cases were distributed relatively evenly through all pediatric age. 2) The monthly distribution showed peak incidence in summertime. 3) Vomiting (66.7%), headache (52.6%) and fever (49.1%) were chiefly complained and definite neck stiffness was observed in 47% of cases 4) Leukocytosis and elevation of erythrocyte sedimentation rate in peripheral blood were not so marked. 5) On cerebrospinal fluid examination, WBC counts were less than 500/mm3 in 91% of cases and glucose concentrations were more than 40 mg/dl in 94.2% and protein concentrations were less than 60 mg/dl in 52% of cases. Significant correlations was noted between CSF WBC counts and protein levels. 6) In acute phase of aseptic meningitis, the mean of CSF protein level was 62.36±35.81 mg/dl, and it showed significant difference as compared with that of control group (39.95 ±51.17 mg/dl). In convalescent phase of aseptic meningitis, the mean of CSF protein level was 39.40 ±25.24 mg/dl with singificant decrease from that of acute phase.

Keywords :Aseptic meningitis; CSF protein level