All issues > Volume 30(1); 1987

Original Article

J Korean Pediatr Soc. 1987;30(1):17-25. Published online January 31, 1987.

Sodium Homeostasis by Neonatal Kidney.

Seung Joo Lee¹

¹Dept, of Pediatrics, Ewha Womans University

Abstract

Sodium homeostasis by neonatal kidney is important during the postnatal adaptation of body fluid. It is mainly dependent to renal function which was differently maturated by gestational and postnatal ages. I studied the postnatal changes of daily Na intake, urine Na, Na balance, FEN a and Serum Na concentration in neonates with different gestational age. In this study, I demonstrated that more increased urinary Na excretion, higher percentage of FENa, more severe and persistent negative Na balance with subsequent hyponatremia develop in group I, preterm infants bom before the 34th gestational weeks, compared to full term infants. Special attention must be paid in very premature with more limited renal tubular reabsorptive function by structural immaturity. Na supplementation is suggested in this very premature by monitoring of urine Na and serum Na concentration until the appropriate positive Na balance for optimal growth is achieved.

Keywords :Na homeostasis, Na balance, FENa, Hyponatremia.