All issues > Volume 29(11); 1986

Case Report

J Korean Pediatr Soc. 1986;29(11):1232-1238. Published online November 30, 1986.

A Case of Chronic Myelogenous Leukemia in a Child Treated in a Interferon.

Ill Soo Ha¹, Jon Lin Rhi¹, Se Jung Sohn¹, Dug Ha Kim¹, Hyo Seop Ahn¹, Chang Yee Hong¹

¹Department of Pediatrics、College of Medicine，Seoul National University

Abstract

A child with Ph^positive chronic myelogenous leukemia was treated with human leukocyte interferon (Hu IFN-alpha). Hematologic remission was obtained in 16 weeks of treatment, and white blood cell count was decreased in number from 115,000 to 9,600. Platelet：count, spleen size, LDH and bone marrow M/E ratio were decreased in parallel, but there was no significant change in serum vitamin B12 level and LAP score. The patient was treated with maintainance dose of Hu IFN-alpha without any significant side effect for 23+weeks.

Keywords :Interferon; Chronic myelogenous leukemia.