All issues > Volume 29(7); 1986

Original Article

J Korean Pediatr Soc. 1986;29(7):740-747. Published online July 31, 1986.

Studies on Type A and Type B Acute Hepatitis in Children.

Moo Young Oh¹, Soon Ho Kim²

¹Department of Pediatrics, In Je Medical College, Paik Hospital, Busan, Korea
²Department of Clinical Pathology, College of Medicine, Busan National University, Busan，Korea

Abstract

The author investigated incidence, age and sex distribution and some liver function tests in 128 cases of type A acute hepatitis and in 62 cases of type B acute hepatitis of children who were admitted to the pediatric ward of Busan In Je Medical college Hospital from January, 1982 to August, 1984. Diagnosis was established clinically and serologically in all patients. Serological HBV markers and anti-HAV (IgM) were determined by radioimmunoassay. The results obtained were summarized as follows: 1) In 194 cases of children with acute hepatitis, incidences of type A and type B acute hepatitis were 66.0X(128/194) and 32.0% (62/194), respectively. 2) In the patients below 5 years of age, the incidence of type B acute hepatitis tended to be higher, as compared with that of type A acute hepatitis, while in the patients of 6 to 11 years of age, the latter was significantly higher, as compared with that in the former. 3) Mean values of AST and ALT activities showed no significant difference between type A and typeB acute hepatitis. But the patients with 50〜200IU/L of ALT activity were more common in type B acute hepatitis, as compared with that in the typeA acute hepatitis, while the patients with above 200IU/L of ALT activity were more common in the latter, as compared with that in the former. 4) Mean values of ALP activity showed no significant difference between type A and type B acute hepatitis. The patients with 13〜30 K-AU of ALP activity were more common in type B acute hepatitis, as compared with that in type A acute hepatitis, while the patients with above 30 K-AU were more common in the latter, as compared with that in the former. 5) Mean values of total bilirubin were no significant difference between type A and type B acute hepatitis. The patients with 2〜4 mg/dl of total bilirubin were more common in type A acute hepatitis, as compared with that in type B acute hepatitis, while the patients with above 10 mg/dl were more common in the latter, as compared with that in the former. 6) Mean value of TTT were higher in type A acute hepatitis, as compared with that in type B acute hepatitis. The percentage of the patients with abnormal TTT values was higher in type A acute hepatitis, as compared with that in type B acutehepatitis.

Keywords :Acute viral hepatitis; Type A; Type B.