All issues > Volume 29(4); 1986

Original Article

J Korean Pediatr Soc. 1986;29(4):381-386. Published online April 30, 1986.

Renovascular Hypertension in Childhood.

Jae Won Song¹, Soo Heun Lim¹, Yong Choi¹, Kwang Wook Ko¹, Chang Yee Hong¹, Kyung Mo Yeon²

¹Dept, of Pediatrics, College of Medicine, Seoul National University
²Dept, of Radiology, College of Medicine, Seoul National University

Abstract

The following results were obtained from a retrospective analysis of 21 cases of renovascular hypertension who were admitted to Pediatric Department, Seoul National University Hospital, during the period from January 1978 to December 1985. 1) Takayasu arteritis was the most common cause (15 out of 21, 71%), and fibromuscular dysplasia of renal artery was confirmed only in two (9.5%) cases. 2) Male to female ratio was 1 to 4.2 with female preponderance. 3) Dyspnea(71 %), headache(57%), abdominal pain(29%), seizure(24%) were the common complaints. Fundus change and cardiomegaly were noted in 41% and 57% respectively. The relatively high incidence of secondary change to hypertension in these cases suggested that our:cases had had rather prolonged hypertension before the diagnosis was made. 4) IVP and renal scan showed abnormalities in 85% and 100% of the cases studied, which were high enough that the both test were very helpful as screening tests in our cases with renovascular hypertension. 5) Conventional antihypertensives such as diurectcs, /9-blockers, hydralazine were not effective at all. On the other hand, captopril, a converting enzyme inhibitor, was very effective in controlling of blood pressure in 7 out of 9 cases used.

Keywords :Renovascular hypertension; Takayasu arteritis; Fibromuscular dysplasia.