All issues > Volume 29(4); 1986

Original Article

J Korean Pediatr Soc. 1986;29(4):361-374. Published online April 30, 1986.

Superoxide Dismutase Activity in Down Syndrom.

Moon Sook Lee¹, Hae Woon Chang¹, Kun Soo Lee¹, Ja Hoon Koo¹, Kun Young Sohn²

¹Department of Pediatrics, School of Medicine, Kyung-Pook National University, Taegu、Korea
²Department of Biochemistry, School of Medicine, Kyung-Pook National University, Taegu、Korea

Abstract

Superoxide dismutase activity of erythrocyte in 20 cases of 21-trisomy Down syndrome between 2 months and 15 years old age and 13 cases of age-matched normal children were checked at Department of Pediatrics and Department of Biochemistry, School of Medicine, Kyung-Pook National University. The results were following: Mean superoxide dismutase activity in normal children was 202.25 U/gmHb and in Down syndrome 291.69 U/gmHb, and the ratio of normal to Down syndrome was 1 : 1.44. There were no statistically significant differences in superoxide dismutase activity acco- rding to age and sex in normal and Down syndrome.

Keywords :Superoxide dismutase; Down syndrome.