All issues > Volume 29(2); 1986

Original Article

J Korean Pediatr Soc. 1986;29(2):178-185. Published online February 28, 1986.

Clinical Study of Acute Glomerulonephritis in Children.

Kyeong Rae Moon¹, Choon Ho Park¹, Sang Kie Kim¹, Jin Heon Kim¹, Chang Soo Ra¹

¹Department of Pediatrics, College of Medicine, Chosun University, Kwangju, Korea

Abstract

From January 1979 to June 1984, 96 cases of acute glomerulonephritis were clinically investigated at the Department of Pediatrics, Chosun University Hospital, and following results were obtained: 1) Male to female ratio was 1.7 : 1, and the age incidence was highest in children from 7 to 9 years (35.4%), with a seasonal peak in Autumn and Winter (66.8%). 2) The most common preceding disease upper respiratory infections (37.5%), and the next was impetigo (11.5%). 3) The most common chief complaints were edema(91.6%), hematuria(51.9%), oligouria (25%), and hypertension greater than 90mmHg in diastolic pressure was in 17.7%. 4) The group A ß-hemolytic streptococci were cultured in 7.3% from throat culture, and Antistreptolysin 0 titers of greater than 333 lodd units was noted in 42.7%. 5) The laboratory findings on admission revealed hematuria(83.2%), proteinuria(83.2%), casts in urine (75.2%), and increased ESR(80.2%) and increased BUN(41.7%) and increased creatinine (57.3%). 6) The mean levels of serum IgG, IgM and IgA were increased than normal levels. 7) The mean serum C3 level was 18.5± 13.4 mg/dl and was lower than normal range (80-125 mg/dl). 8) Complications were seen in 5.2%, and were lower than reports. 9) Gross hematuria, edema and hypertension disappered in the most of the patients within 2 weeks.

Keywords :Acute glomerulonephritis; Immunoglobulins; Cs.