All issues > Volume 29(1); 1986

Case Report

J Korean Pediatr Soc. 1986;29(1):101-107. Published online January 31, 1986.

2 Cases of Herpes Simplex Virus Infection in the neonates.

Kyung Hyo Kim¹, Jeong Wan Seo¹, Kyung Hee Kim¹, Keun Lee¹, Ki Sook Hong², Mi Ae Lee², Woon Sup Han², Ok Kyung Kim², Yung Oh Shin³, Sung Bok Paik³

¹Department of Pediatrics, College of Medicine, Ewha Wamans University, Seoul，Korea
²Department of Pathology, College of Medicine, Ewha Wamans University, Seoul，Korea
³Department of Virology, National Institute of Health, Seoul, Korea

Abstract

Herpes simplex virus infection in the newborn is generally thought to be associated with a grave prognosis in terms of mortality and severe neurologic sequelae among survivors. Most neonatal herpes infection are due to type 2 herpes virus hominis, acquired either by ascending infection from the mother’s genital area to the intrauterine infant after premature rupture of membrame, or by spread to the infant during delivery through the birth canal of an infected mother. This is a report of type 2 herpes simplex virus infection which developed in twin neonates and confirmed by viral culture. They were expired and autopsies were done. A brief review of related literature was added.

Keywords :Neonatal herpes simplex virus infection.