All issues > Volume 28(12); 1985

Case Report

J Korean Pediatr Soc. 1985;28(12):1231-1237. Published online December 31, 1985.

Myelodysplastic syndrome Transformed into Erythroleukemia.

Sun Hee Kim¹, Don Hee Ahn¹, Keun Chan Sohn¹, Jung Il Suh², Jung Hee Um³, Hea Ran Park³

¹Department of Pediatrics, National Medical Center, Seoul, Korea
²Department of Pathology, National Medical Center, Seoul, Korea
³Department of Clinical Biochemistry, National Medical Center, Seoul, Korea

Abstract

Myelodysplastic syndrome is a disorder of the marrow stem cell characterized initially by ineffective erythropoiesis, an abnormal bone marrow, and peripheral blood cytopjenia. Recently MDS was classified into 5 subtypes by the F rench-American-British (FAB) Cooperative Group: (1) Refractory anemia(R.A.), (2) RA with ring sideroblast, (3) RA with excess of blast(RAEB), (4) Chronic myelomonocytic leukemia (CMML) and (5) RAEB in transformation. We observed one case of MDS(RAEB) which transformed into erythroleukemia after 17 months and report that case with autopsy finding.

Keywords :Myelodysplastic syndrome