All issues > Volume 28(11); 1985

Case Report

J Korean Pediatr Soc. 1985;28(11):1153-1157. Published online November 30, 1985.

Three Cases of Glanzmann's Thrombasthenia.

Sung In Baek¹, Myung Chul Hyun¹, Haeng Mi Kim¹, Kun Soo Lee¹, Doo Hong Ahn¹, Hyo Jin Chun², Jay Sik Kim²

¹Department of Pediatrics, School of Medicine, Kyungpook National University, Taegut Korea
²Department of Clinical Pathology, School of Medicine, Kyungpook National University, Taegut Korea

Abstract

We experienced 3 cases of Glanzmann' s thrombasthenia of 2 year-old boy, 4 year-old boy, and 5 year-old girlt who represented with frequent epistaxis and petechia. The later two of them are brother and sister.Laboratory findings were characterized by normal platelet counts, markedly diminished clot retraction, prolonged bleeding time, positive Rumpel-Leede test, abnormal platelet adhesion to glass, and complete failure of platelet aggregation by ADP and collagen. We are reporting our experience of 3 cases with a review of literatures.

Keywords :Glanzmann’s thrombasthenia; Platelet aggregation; Autosomal recessive trait;Platelet function test