All issues > Volume 28(9); 1985

Original Article

J Korean Pediatr Soc. 1985;28(9):861-868. Published online September 30, 1985.

The clinical Study on Mucocutaneous Lymphnode Syndrome.

H D Cha, B Ahn, S H Kim, T C Kwon, C M Knag

¹Department of Pediatrics,School of Medicine,Keimyung University, Taegu,Korea

Abstract

Mucocutaneous lymphnode syndrome (Kawasaki Disease) is a newly described acute symptom complex of children that was first recognized and described by Dr. Tomisuku Kawasaki in Japan. This syndrome recently was reported from various areas other than Japan, mainly U.S.A and Korea. Authors observed the clinical and epidemiological features on 68 cases of mucocutaneous lymphnode syndrome which were admitted to Pediatric department of Dong San Hospital, Keimyung University, Taegu, Korea during the period of five years from July 1979 through June 1984. The following results were obtained: 1)57.3% of cases were observed between 6~24 months of age. 2)50% of cases were found in cold season between November-February. 3)Male to Female ratio was 1.9 : 1. 4)The incidence of principal symptoms were fever (100%), lips and oral mucosal change (100%), bilateral conjunctival injection (72.0%), changes in extremities (induration of palm and sole 67.6%, desquamation 77.9%) polymorphous erythematous maculopapular rashes (63.2%) and cervical lymphadnopathy (63.2%) in order. The mean duration of fever was 13.1 days. 5) In laboratory findings, anemia (36.8%), leukocytosis (54.4%), thrombocytosis (46.0%) increased ESR(96.7%) and positive CRP(90.7%) were found. 6)Cardiac abnormalities were found in 12.8% by ECG, 24.1% by Echocardiogram. 7)Ultrasonogram of gall bladder was done on 13 cases, of which 3 cases(23.0%) had gall bladder hydrops. 8) All cases were treated with aspirin. 63 cases(92.6%) were improved and follow up check was failed in 5 cases.

Keywords :Mucocutaneous lymphnode syndrome