All issues > Volume 28(7); 1985

Original Article

J Korean Pediatr Soc. 1985;28(7):653-662. Published online July 31, 1985.

Clinical Observation of Profiles of Serologic Markers in Hepatitis B.

H Y Ahn, S T Kim, S G Cho, Y Y Choi, J S Ma, C Sohn

¹Department of Pediatrics, Chonnam University, Medical School, Kwangju,Korea

Abstract

Serologic markers of hepatitis B virus were detected by Enzymeimmunoassay in acute(88 cases in 68 patients) and chronic (19 cases in 6 patients) hepatitis B. 1)Positive rate of HBsAg was highest (acute 64.5%, chronic 89.4%) in 5 serologic markers and AntiHBe or AntiHBs were not detected in chronic cases. 2)18 serologic profiles (I~XXIII) were observed, of these common type was 78.4% and unusual type 21.4%. 3)Cases with Anti HBc positive only were 17% of acute and 10.5 % of chronic hetpaitis B. Positive rate of HBeAg in HBsAg negative cases of acute hepatitis B was 2.3%. 4)In acute cases, positive rate of HBsAg with AntiHBs was 10.2% and at that cases S/P ratio of HBsAg was 0.16. In chronic cases with HBsAg positive, S/P ratio of HBsAg was 1.23(p<.001).

Keywords :Serologic markers; Hepatits B virus; Positive rate; S/P ratio