All issues > Volume 28(2); 1985

Original Article

J Korean Pediatr Soc. 1985;28(2):140-146. Published online February 28, 1985.

Clinical, epidemiological, and serological observation on human rotavirus gastroenteritis in infants and children.

Chin Moo Kang

¹Department of Pediatrics, Keimyung University^ School of Medicine,Taegu,Korea

Abstract

The author studied 115 infants with watery diarrhea, admitted to the Pediatric Department of Dorg San Medical Center during the period of 9 months from October 1982 through June 1983 and dsveloped an Enzyme lirked immunosorbent assay to detect human rota virus antigen for all patients and clinical, epidemiologic, and laboratory studies were done. The results were as follows: 1)76 cases(66.09%) were between 6~24 months of age. 2)Most of the patients were seen during cold season in October(25.22%) and November (39.13%). 3)Vomiting was noted in 88 cases(76.52%) and dehydration in 75 cases(65.22%) of which 87.83% were isotonic. 4)URI symptoms such as cough(45.09%), pharyngeal injection(22.6%) and runny nose (11.3%) were noted. 5)HRV antigen was detected in 72 cases(62.61%) by ELISA. Positive rate for antigen was highest in 6~12 months of age group(71.43%) and in November and December. 6) No cases were died and no sequala was developed. Mean length of total illness was 8.2 days. In view of that there was no significant difference in clinical symptoms and epidemiological pattern between antigen positive and antigen negative groups, we may conclude that acute epidemic gastroenteritis during the months of October through December in this country is the diarrhea caused by HRV.

Keywords :Human rotavirus gastroenteritis;ELISA