All issues > Volume 27(11); 1984

Case Report

J Korean Pediatr Soc. 1984;27(11):1141-1146. Published online November 30, 1984.

A Case of Chronic Granulomatous Disease.

C H Park¹, M R Roh¹, S C Park¹, J O Park¹, D H Lee¹, S J Lee¹

¹Department of Pediatrics, College of Medicine，Soon Chun Hyang University, Seoul, Korea

Abstract

Chronic granulomatous disease is characterized by an inability of patients* leukocytes to generate hydrogen peroxide and to kill non-peroxide forming bacteria, such as staphylococci, E. coli and serratiae etc. We experienced a case of chronic granulomatous disease with recurrent pyogenic infection. It was diagnosed by clinical findings and laboratory examinations including NBT test. Clin- ical findings showed persistent diarrhea since birth, recurrent bacterial pneumonia, perianal abscess, skin infection, supraclavicular lymphadenopathy, eczema, osteomyelitis, and anemia. NBT test was 0%. We made a brief review of literature.

Keywords :Chronic granulomatous disease.