All issues > Volume 27(6); 1984

Original Article

J Korean Pediatr Soc. 1984;27(6):603-609. Published online June 30, 1984.

Clinical Study of Wilms' Tumor .

Myung Hyun Lee, In Sil Lee, Hyo Seop Ahn, Chang Yee Hong

¹Department of Pediatrics, College of Medicine, Seoul National University

Abstract

Thirty-five cases of Wilms tumor treated at the Seoul National University Hospital from 1969 to 1983, were analyzed and the results are as follows: 1)Ages at nephrectomy were from 1 monh. to 11 years and 8 months. The mean, age was 3 years and 4 months and the median was 2 years and 9 months. The sex ratio of male to female was 1 : 1.5. 2)There were 16 cases of left-sided tumor and 19 cases of right-side tumor. 3)Congenital defects were found in 20% of the cases and genitourinary anomalies were most common. 4)The most frequently encountered symptoms were abdominal tumor/distension(97.1%), fever, hematuria, abdominal pain, vomiting and hypertension. 5)Chest Xray showed pulmonary nodules in 5 cases, and intravenous pyelogram showed intrarenal mass in 26 cases(74.3%). 6)The distribution of patients according to stage using NWTS staging system were 11, 9, 7 and 8 cases of stage I, K, K and ]y, respectively. 7)Local recurrences and/or distant metastases were observed in 14 cases: 8 of them presented with metastases at initial diagnosis. Involved organs were ung(57.1%), liver, abdomen excluding liver, bond marrow and subcutaneous tissues. 8)The 2-year survival rates of the 33 patients treated were 67.0%. The patients under 2 years of age have higher 2 years survival than the patients over 2 years of age. Two-year survival rates of the patients in stage I were 87.1%, and the patients in stage IV were 37,3%(P
Keywords :Wilms tumor; Two-year survival rate