All issues > Volume 27(2); 1984

Original Article

J Korean Pediatr Soc. 1984;27(2):135-145. Published online February 28, 1984.

Cardiac Involvement of Kawasaki Disease.

Gu Soo Kim, Kyu Gap Hwang, Byung Kwan Sohn, Jung Yun Choi, Yong Soo Yun, Chang Yee Hong

¹Department of Pediatrics, College of Medicine, Seoul National University, Seoul, Korea

Abstract

Twenty-nine cases of Kawasaki disease, who were admitted to the Dept, of Pediatrics, Seoul National University Hospital, were evaluated on the incidence, clinical signs and laboratory findings of cardiovascular system. Among them two patients were excluded from the incidence of cardiac involvement: One with incomplete study died at home on 22nd day after the onset, and the other was referred because of already detected cardiac involvement. Cardiac involvement revealed, heart murmur in two patients(7.4%), cardiac enlargement in four patients(14.8%) by chest roentgenogram, electrocardiographic abnormalities in 16 patients(59.3%), pericardial effusion in three patients (11.1%) by echocardiogram and coronary aneurysms in five patients(18.5%) by 2-D echocardiogram and/or coronary angiography. The autopsy findings of one patient who died showed right coronary aneurysmal rupture, hemopericardium, both coronary aneurysms, coronary arterial thrombosis, pericardial effusion, coronary arteritis, myocarditis, focal myocardial fibrosis and pericarditis. In the other patient referred due to congestive heart failure, electrocardiogram showed myocardial infarction. M-mode echocardiogram revealed congestive cardiomyopathy and left ventriculography identified mitral regurgitation. There was no statistically significant difference in clinical and laboratory findings such as duration of fever, degree of anemia, leukocytosis, thrombocytosis, elevation of ESR, positive CRP, and electrocardiographic abnormalities, between the patients with aneuryms and without aneurysm. But aneurysm affected more frequently male children than female in a ratio of 5 : 1.

Keywords :MCLS; cardiac involvement; coronary aneurysm