All issues > Volume 26(12); 1983

Case Report

J Korean Pediatr Soc. 1983;26(12):1220-1225. Published online December 31, 1983.

A Case of Histiocytic Medullary Reticulosis in 17 Month-old Child.

Oh Kyung Lee¹, Wan Seob Kim¹, Myung Ho Lee¹, Sung Seek Lee¹, Sook Ja Park²

¹Depart, of Pediatrics，Jeonju Presbyterian Medical Center
²Depart, of Clinical Pathology, Jeonju Presbyterian Medical Center

Abstract

Histiocytic medullary reticulosis(HMR) is a rare, uniformly fatal, acute disease of the reticuloen dothelial system. Major features are fever, malaise, weakness, weight loss, lymphadenopathy, hepatosplenomegaly, jaundice and purpura. Common laboratory finding is severe pancytopenia. Cardinal pathologic feature is proliferation of atypical, neoplastic, erythrophagocytic histiocytes. Recently we experienced a case of HMR in 17 month-old male child. The clinical findings and hematologic features were identical to those of previously documented HMR. In this report, we illustrate pertinent clinical and pathologic features of this disease in early childhood and review the literature concerning this disease.

Keywords :Histiocytic medullary reticulosis.