All issues > Volume 26(7); 1983

Original Article

J Korean Pediatr Soc. 1983;26(7):687-695. Published online July 31, 1983.

Clinical Observations of 14 cases of Mucocutaneous Lymh Node Syndrome.

Geom Hyun Jang¹, Young Hae Lee¹, Chang Hee Choi¹, Kyu Eun Lee¹

¹Department of Pediatrics, Seoul Adventist Hospital, Seoul, Korea

Abstract

We observed clinically 14 cases of mucocutaneous lymph node syndrome who were admitted to the Department of Pediatrics, Seoul Adventist Hospital from Jan. 1981 to June 1983 and following results were obtained. 1. This syndrome developed in mainly under 2 years old of age with predominant in male. 2. The main clinical manifestations are as follows: 1) Fever lasting from one to two weeks. 2) Bilateral conjunctival injection. 3) Erythematous rash, mainly in trunk. 4) Diffuse reddening of lips, which become dry, fissured, diffuse reddness of oropharyn-geal mucosa, strawberry tongue. 5) Initial reddness of the palms and soles with indurative edema followed in the convalescent stage by striking desquamation beginning in the junction of the nails and skin of the tips of the fingers and toes. 6) Mainly unilateral cervical lymphadenopathy. 3. Laboratory findings are mild anemia, leukocytosis with shift to the left, increased ESR, positive CRP, normal ASO, proteinuria and pyuria. 4. Other findings include vomiting, diarrhea, arthralgia, convulsion, and bronchopneumonia in 5 cases. 5. Concerning the E.K.G., sinus tachycardia was present in 5 cases while the others were within normal limit. 6. During the acute febrile phase, we used aspirin in high dose (100 mg/kg/24 hr) and once fever, rash, and acute symptoms have been controlled, we decreased the aspirin to low dose(30 mg/kg/24 hr). 7. There was no complication and completely recovered in all cases.

Keywords :MCLS; clinical observation