All issues > Volume 26(3); 1983

Case Report

J Korean Pediatr Soc. 1983;26(3):289-284. Published online March 31, 1983.

Two Cases of Di Guglielmo Syndrome.

Seok Ku Kim¹, Seong Ja Jeon¹, Chul Lee¹, Myung Ho Lee¹, Sook Ja Park²

¹Department of Pediatrics, Presbyterian Medical Center, Jeonju，Korea
²Department of Clinical Pathology，Presbyterian Medical Center, Jeonju，Korea

Abstract

Di Guglielmo Syndrome is a relatively rare disease in childhood and refers to an acute or chronic myeloproliferative disorder in which erythrocytes and their precursors are the cells predominantly involved in the leukemic process. We experienced two cases of Di Guglielmo syndrome, an llyear-old girl and a 14 year-old boy, who had the chief complaints of severe anemia, fever, dizziness and general malasia. The Bone marrow revealed an increased pattern in the populaton of erythroid cells including typical rubriblast, prorubriblast and bizarre multinucleated rubriblast. One case was a stage of acute myelocytic leukemia, the other case was a stage of erythroleukemia.

Keywords :Di Guglielmo syndrome.