All issues > Volume 26(2); 1983

Case Report

J Korean Pediatr Soc. 1983;26(2):203-208. Published online February 28, 1983.

9 Case of Klinefelter Syndrome.

Hack Joo Cha¹, Jong Sub Lee¹, Ki Bok Kim¹

¹Department of Pediatrics, Kwangju Christian Hospital

Abstract

A cytogenetic study was carried out on 9 cases of Klinefelter Syndrome referred to the Department during a-3-year period from February, 1979 through February, 1982. The following results were obtained. 1) The distribution of age at the time of definite diagnosis was between the age of 17 and 31, average being 23.8 years. 2) Mean height was 173.2 cm. 3) Chief complaints were small genitalia (4 cases), gynecomastia (3 cases), small genitalia ane gynecomastia (1 case), and sexual dysfunction (1 case). 4) The most frequent symptoms were soft skin, no beard, small testes, sexual dysfunction, absent or scanty pubic hair, gynecomastia, small penis, and loss of axillary hair, in decreasing order. 5) Chromosome analysis revealed 47, XXY in 5 cases, and 46, XY in 4. 6) Barr bodies of buccal smear from 5 cases of 47, XXY were positive in 68%, 75.8%, 48%, 53%, and 66% of cells respectively.

Keywords :Klinefelter Syndrome.