All issues > Volume 25(12); 1982

Case Report

J Korean Pediatr Soc. 1982;25(12):1289-1294. Published online December 31, 1982.

Two Case of Ginaotti-Crosti Syndrome.

Jae Ho Lee¹, Soon Ung Kang¹, Jeong Kee Seo¹, Hyo Seop Ahn¹, Kwng Wook Ko¹, Won Suk Kim²

¹Department of Pediatrics, College of Medicine, Seoul National University
²Department of Dermatology, College of Medicine，Seoul National Uuiversity

Abstract

The Gianotti-Crosti syndrome is an. infrequently recognized disorder with distinctive clinical features. We have experienced two cases of Gianotti-Crosti syndrome diagnosed by clinical manifestation, laboratory data and histopathologic finding of skin. Case one; An 18-month-old girl was admitted to the pediatric ward with the chief complaint of erythematous rash. Its onset was preceded by an. upper respiratory tract infection. She had a wide spread erythematous papular skin eruption of non-itching and of 1 to 5mm in diameter. It spread from the lower extremity, buttock, upper extremity to face. Associated finding were cervical lymphadenopathy, anicteric hepatitis, which lasted about 2 months, and HBs antigenemia. Histopathological examination of a biopsy specimen, obtained from the lower leg showed focal parakeratosis with mild spongiosis of epidermis and mononuclear cell infi- ltration in the upper dermis. Case two; A 14-year-old boy was admitted with the chief complaints of high fever and an. erythematous papular skin rash. The fever was controlled soon. He had a wide spread erythematous papular skin eruption of non-itching on the face, limbs and buttock. The significant findings were cervical lymphadenopathy, anicteric hepatitis and HBs antigenemia. We report the two cases of Gianotti-Crosti syndrome with review of the related literature.

Keywords :Gianotti-Crosti syndrome; HBs antigenemia.