All issues > Volume 25(10); 1982

Original Article

J Korean Pediatr Soc. 1982;25(10):1039-1045. Published online October 31, 1982.

A Study of Correlation between Bilirubin Leel of Cord Blood and Neonatal Hyperbilirubinemia.

Hwan Sup Kang, Chang Il Ahn

¹Department of Pediatrics, College of Medicine, Kyung Hee University, Seoul，Korea

Abstract

For adequate management and prevention of severe sequellae of neonatal hyperbilirubinemia^ such as kernicterus, early detection of its presence is very important in fields of neonatology. The author studied the correlation between bilirubin level of the cord blood and neonatal hyperbilirubinemia in random sampled 169 neonates of 729 deliveries during a period of five months since December 1981 at the Kyung Hee University Hospital. The blood groups and types (ABO, Rh) of both neonates and mothers, hemoglobin, hematocrit, and reticulocyte values of the cord blood were determined, and direct Coombs' tests were performed in neon- ates with documented hyperbilirubinemia. The results were obtained as follows: 1. The total cord bilirubin level of the 169 neonates averaged 1.42+0.40mg/dl, while that of ABO incompatibility group 5.17±3.89mg/dl, that of treated group 1.63±0.35mg/dl and not treated 1.40±0.42mg/dl(Treated group: Not treated group = p<0.05). 2. Visible jaundice of the treated group ；appeared at 3.05±l. 35 days of life with total serum bilirubin level of 10.92±1.94mg/dl and the highest level was noted at 4. 85±1.31days of life with 16.49±1.78mg/dl. 3. The neonates who were managed for hyperbilirubinemia were 20 of 169(11.8%).Visible jaundice of the jaundiced group appeared at third to fourth day of life(90%), and appeared within 12 hours of life in three fourth of ABO incompatibility group. 4. The results obtained indicated that the determination of total bilirubin level, blood grouping, and direct Coombs’ test of cord blood were valuable^for early detection of hyperbili rubinemia in case of maternal “O” blood group having suspiciously ABO incompatibility with neonates.

Keywords :Hyperbilirubinemia, Cord blood, Neonatal Jaundice.