All issues > Volume 25(9); 1982

Case Report

J Korean Pediatr Soc. 1982;25(9):945-948. Published online September 30, 1982.

A Case of Neonatal Hemolytic Disease due to Anti-c Isoimmunization

Hwan Sup Kang, Hyo Sup Joo, Chong Woo Bae, Suk Chul Kang, Chang Il Ahn

¹Department of Pediatrics，College of Medicine，Kyung Hee University，Seoul, Korea

Abstract

A 40 hours old female neonate was admitted to the Pediatric Ward of Kyung Hee Unive- rsity Hospital due to severe jaundice. Laboratory work up showed typical pictures of immune hemolytic anemia. But there was no incompatibility of ABO and Rh(D) systems between the baby and mother. Minor blood groups were examined by Reagent Red Cells Selectogen and Antigram. High titer (1 : 125) of anti-c antibody was detected in mother’s serum. Emergency exchange transfusion was performed with A, Rh(D) (+) blood, resulted in excellent recovery. This case is the first report of c-isoimmunization in Korean neonate.

Keywords :Neonatal hemolytic disease, Minor group incompatibility, Anti-C isoimmunization